glp 1 receptor agonists GLP-1 and next-generation metabolic hormone therapies in chronic kidney disease Potential Use of GLP-1 and
Description
Firstly, there was no head-to-head CVOT directly comparing these antidiabetic drug classes

Side Effects : GLP-1 often causes nausea and headaches, while Metformin leads to diarrhea and bloating

About the author

While capsules can be administered by mouth to pigs, it was decided to introduce the capsule directly into the jejunum, since the gastric transit in the pig can be variable and of long duration, the pig stomach is more fermenting than that of a human, and the pH of the stomach is high, to the extent that enteric coating of the capsule may not give adequate protection
