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After propensity score matching (18,386 patients), researchers found: Patients receiving tirzepatide were 1.76 times more likely to achieve 5% weight loss 2.54 times more likely to achieve 10% weight loss 3.24 times more likely to achieve 15% weight loss At 12 months, the difference in weight change was 6.9 percentage points favoring tirzepatide

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Other common side effects include diarrhea, constipation, vomiting, abdominal pain, and decreased appetite (which is partly how the medication works)

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