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As such, therapy in low-risk individuals should be guided by treatment effects on metabolic outcomes, such as HbA 1c reduction and weight loss, rather than cardiovascular outcomes
The additional mechanism of action could reignite progress and support continued movement toward health goals
The STEP clinical trial series demonstrated that weekly semaglutide 2.4 mg achieved 16.8% average weight loss in patients with obesity but without diabetes over 68 weeks, significantly better than placebo
Although not as frequent as gastrointestinal issues, awareness of them is important for comprehensive care
