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Side effects typical of GLP-1 RAs include:22 Nausea Bloating Vomiting Diarrhea Abdominal pain Belching Flatulence Most of these symptoms are associated with these drugs' ability to slow down your digestion.12 As you acclimate to your bodys changing digestive rhythm and consume fewer calories per meal, these side effects tend to dissipate

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In the event of an overdose, it is reasonable to employ supportive measures, e.g., remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring (including obtaining an electrocardiogram), and institute supportive therapy as indicated by the patient's clinical status

When used with insulin or sulfonylureas, there is an increased risk of low blood sugar (hypoglycemia)