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doi: 10.1093/toxsci/kfp126 [DOI] [PubMed] [Google Scholar] 107.Lang BT, Yan Y, Dempsey RJ, Vemuganti R

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Common pharmacological triggers include antihistamines, antidopaminergic antiemetics, most antidepressants (particularly selective serotonin reuptake inhibitors and tricyclic antidepressants), and some antipsychotic medications

For example, in obese mice, 5-HTR 2B is upregulated and found to be responsible for increasing the lipolysis in the visceral adipose tissue, which subsequently worsens insulin resistance through excess free fatty acids [172]