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Lixisenatide is effective and safe as add-on treatment to basal insulin in Asian individuals with type 2 diabetes and different body mass indices: A pooled analysis of data from the GetGoal Studies

Semaglutide restored GSK3-Drp1 signalling, maintained mitochondrial membrane potential, and decreased mitochondrial fragmentation in primary cardiomyocytes via GLP-1R activation

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GCs antagonize the metabolic effects of insulin, particularly in the postprandial state through the induction of enzymes that promote gluconeogenesis, increased lipolysis and proteolysis, increased mitochondrial activity, the enhancement of the effects of counterregulatory hormones, such as glucagon and epinephrine, and the induction of insulin resistance via the nuclear peroxisome proliferator-activated receptor (PPAR) [4,21,25]