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Noteworthy, neither PRA nor plasma aldosterone significantly changed after six months of treatment, confirming the transient diuretic effect of SGLT2-i
They also directly address the hormonal side of PCOS by helping to lower androgen levels, which can reduce frustrating symptoms like acne and unwanted hair growth
doi:10.1001/jama.281.3.235 61
Ensure adequate protein intake (generally 0.8-1.0 grams per kilogram of body weight daily per US Dietary Guidelines, though patients with chronic kidney disease should follow their healthcare provider's specific recommendations)
