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Despite supply shortages, the GLP-1 drugs by the two companies saw their sales surge in the first quarter of the year, and competitors are still trying to catch up.

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Although some amelioration of inflammation has been seen, these drugs did not improve the fibrosis component of NASH

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Pfizer ~$60B+ annual revenue scale Rebuilding pipeline via acquisitions + obesity/oral therapies race Focus: post-COVID repositioning into oncology & specialty 2

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Retatrutide 30

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