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glp-1 receptor agonist creatine interaction and Medications: Muscle Preservation Strategy Creatine and GLP-1 Medications: Safety
Description
Therefore, if a new oral drug in development is intended to be co-administered with a GLP-1 agonist, we highly recommend conducting a healthy volunteer drug-drug interaction prior to Phase 3 trials to characterize the impact on the PK of the candidate new drug

Pulm Pharmacol Ther (2021) 67:102003

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Yes, GLP-1 medications work best when combined with healthy lifestyle changes
