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The clearest signal comes straight from FDA prescribing information for semaglutide products, which notes that there have been postmarketing reports of acute kidney injury, in some cases requiring hemodialysis, with the majority of reported events occurring in patients who experienced gastrointestinal reactions leading to dehydration such as nausea, vomiting, or diarrhea

In 2023, after years of yo-yoing weight, frivolous calorie-counting, and a relentless binge-restrict cycle, I started an intensive treatment teamseeing a therapist, a psychiatrist, and a nutritionist who specializes in eating disordersto address the roots of my disorder and my food-related fears

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Why this matters 1 Retatrutide delivered some of the most impressive weight loss seen in Phase 3 obesity studies In TRIUMPH-1, participants receiving retatrutide 12 mg lost an average of 70.3 pounds (28.3%) over 80 weeks