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Liraglutide suppresses TNF--induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis

Differentiation amongst these agents is important, and there are several factors that will make assets from smaller companies attractive: 1) oral and infrequent dosing regimens, 2) ability to improve cardiometabolic outcomes along with weight loss, and 3) reduced GI side effects

For patients taking antihypertensive medications, dose adjustments may be necessary as weight loss progresses and blood pressure naturally declines

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