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25 however, emerging evidence supports the notion that intestinal SMCs are affected functionally and structurally by most inflammatory conditions involving the intestine leading to altered morphology and contractile behavior, and secretion of various inflammatory mediators

Beyond the general DKD risk conferred by obesity, fat accumulation in depots anatomically close to the kidney as well as intrakidney fat accumulation has been linked to kidney disease

On GLP-1, digestion is slower and less predictable

Hajek T, Calkin C, Blagdon R, Slaney C, Uher R, Alda M
