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However, it has been suggested that nicotine may augment the effects of leptin in the brain by enhancing leptin binding or increasing the sensitivity of downstream transduction cascades

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"'Nic-sick,' as it's being called, refers to non-specific symptoms of exposure to nicotine, especially if it is above someone's tolerance," said Panagis Galiatsatos, M.D., MHS, a volunteer medical spokesperson for the American Lung Association and assistant professor at Johns Hopkins School of Medicine explained

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