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You only have to ensure that you use vapes moderately to avoid overdosing yourself with nicotine, a highly addictive substance
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To obtain 2mg of nicotine, you would want to smoke about 2 cigarettes, since each stick typically delivers around 1mg of nicotine
For the study, then, Shields and his co-authors reviewed hundreds of published scientific papers, including human studies, animal studies and smoking machine studies
