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For (a) frequency of useoperationalized as the number of use days in a given periodappropriate items in several short questionnaires (e.g., CUDITR (Adamson et al., 2010), ASSIST (WHO Assist Working Group, 2002)) are available

Cinnamon, vanilla and butter flavoring chemicals were the most toxic but our research showed that mixing flavors of e-liquids caused by far the most toxicity to white blood cells. Senior author, Dr Irfan Rahman, says he hopes this new data will provide insights into understanding the harmful effects of flavored e-juices without nicotine

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