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Furthermore, cigarette smoke was shown to reduce major histocompatibility class I (MHC I) antigen presentation by suppressing the activity of immunoproteasome [214]

Additional genes involved include the dopamine D4 receptor, the dopamine transporter (SLC6A3), the serotonin transporter (SLC6A4), and neurexin-1 (NRXN1)

Other herbal remedies like lobelia have also been used in smoking cessation
How Common Is Parosmia
