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Using perforated-patch recording from VTA DA neurons, we found that bath application of 1 M nicotine increased the action potential firing frequency to 242 87 % of control (Fig 1a, 1c
Results: At baseline, the estimated amount of cannabis per joint (0.280.23 g) was double the actual amount (0.140.12 g) ( p =0.003, d =0.723)

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