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The smoke from cigarette combustion contains a high level of free radicals that can induce oxidative injury, cell membrane destruction, and inflammation within lung tissues (Munnia et al., 2006)

Addressing the evidence for FDA nicotine replacement therapy label changes: a policy statement of the Association for the Treatment of Tobacco use and Dependence and the Society for Research on Nicotine and Tobacco
When it came to why, both men started with the kinds of reasons you might hear anywhere

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