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Cigarette alternatives have to be appealing to catch on, and current F.D.A.-approved replacementsnicotine patches, inhalers, gumare designed to achieve a bare minimum of satisfaction

A study published in Nature found that smoking impairs the immune response, increasing the risk of infections, cancers, and autoimmune diseases

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They found that WIN decreased the cell viability in both LNCaP and the NE differentiated cells, and when they incubated the LNCaP cell line with WIN, it showed a significant decrease in the NE markers in the resulting NE cells (106)