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Early in the development of cancer, the abnormal growth of cells begins in one particular location in the body (usually where the cells with DNA damage are located) and produces a tumor
In most homes, what people might call a fire alarm is usually a set of battery- or mainspowered smoke detectors rather than a full system

Cigarette smoke exposure is often chronic, building up day after day and year after year
Occupation status was coded based on self-reported current working status and educational status, resulting in 11 categories
