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Secondly, topical applications to control pain and swelling, such as lidocaine and steroid cream are usually recommended, in addition to oral anti-histamines

Nicotine activates the mesocortical and mesolimbic dopaminergic pathways, releasing dopamine and noradrenaline 10 , 11

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We compared different methods of administrating nicotine, then explained its mechanism of action and the consequences of chronic use
