Memorandum D18-2-1
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This was supported by a 2022 systematic review, which suggested that non-tobacco nicotine pouches have a relatively low risk of cancer compared to other nicotine products (see Figure 3) 10
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Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: Summary and implications
Along with the saltiness, there's still the spice you get with most tobacco strains
