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The "dry puff" condition, when the wick isn't sufficiently saturated, creates even higher levels of toxic compounds

Only individuals with an intention to quit participate in such programs, which limits the generalizability of the results
"Women and the global tobacco epidemic: nurses call to action", International Nursing Review 50 (2003): 215-228 "The Tobacco Atlas"
Chemicals Irritate the Wound Cigarette smoke contains thousands of chemicals, many of which are toxic to healing tissues
