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Based on the number of innovations we found in this study, we would encourage all governments considering implementing plain packaging legislation to consider how tobacco companies have adapted to the legislation in other countries and where possible, close any remaining loopholes. Philip Morris International, which owns Marlboro, did not respond to requests for comment

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In addition, nicotine increases the adhesion of platelets, which leads to the occlusion of small arteries supplying blood to the healing wound and hence causes tissue ischemia, thereby hampering the healing process