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Dimensions: 6744 x 4502 px | 57.1 x 38.1 cm | 22.5 x 15 inches | 300dpi Date taken: 7 September 2019 Location: united kingdom

These studies suggest that small molecules that directly target allosteric sites on GABA A R engaged by 2-AG and possibly CBD, or by inhibiting 2-AG hydrolysis, (e.g., with ABHD6 inhibitors) represent promising therapeutic approaches to reduce enhanced excitatory transmission and treat select neurological diseases, including epilepsy 49