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Laboratory studies reveal TB-500 reduces production of inflammatory mediators including TNF- and IL-1 by 55% while enhancing anti-inflammatory IL-10 and TGF- expression, creating balanced immune responses that clear damaged tissue while supporting regeneration
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However, in the group that received pretreatment with GHK-Cu, the pathological changes in lung tissues were markedly mitigated, as evidenced by the significantly reduced lung injury score (Figure 5G)
Thyroid issues, such as risk of C-cell tumors, have been seen in animal studies (but not yet humans)
