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The synthesis of creatine from glycine in the skeletal muscle of fish may promote more efficient coupling with local energy metabolism for physiological functions (e.g., constant swimming [32]) when compared with terrestrial mammals and birds, because guanidinoacetate is formed and further converted into creatine in the same muscle fiber

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503 Polarity switching is regularly used in profiling methods

doi: 10.1186/1471-2172-14-28
