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Many cells remaining to protect creating larger therapeutic window

(B) The ATP7B protein, known as ATPase copper-transporting beta, contains a phosphatase domain, a phosphorylation domain, an ATP binding domain, a metal binding domain, and eight transmembrane segments

Its primary value may be in accelerating fracture healing rather than preventing bone loss

This is not surprising given that MRS has been historically used to study (a) high-concentration and easily detectable metabolites at lower field strengths, such as N-acetylaspartate, choline, creatine and myo-inositol (Cleeland et al., 2019, Huibregtse et al., 2021), and (b) low-concentration non-GSH metabolites such as gamma-aminobutyric acid and glutamate (Runia et al., 2022)