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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
Mutations and GST pulldown were used to validate the model, which serves as a good example of rational design
This mechanism promotes early satiety signals and reduces the rate of nutrient absorption, leading to flattened postprandial glucose excursions and reduced caloric intake
doi:10.1007/s10628-005-0057-z
