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Currently, no FDA-approved assays are available for quantifying key RCD pathway activation markers (such as GSDMD-N fragment for pyroptosis, phosphorylated MLKL for necroptosis) in clinical practice, making accurate patient stratification difficult (178, 179)

Curcumin inhibited proliferation and induced apoptosis in chronic myeloid leukemia cell lines, particularly K562

Experimental evidence shows that alcohol consumption does indeed result in significant hypoxia in perivenous hepatocytes (hepatocytes that are located close to the vein where the cleansed blood exits the liver)

In their experimental study on azoxymethane-induced hepatotoxicity in mice, Bmeur et al