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K.SammiS

217 In short, based on the fact that cell proliferation-related receptors are overexpressed in tumor cells but are not expressed or underexpressed in normal cells, NDCDS can be designed to target the corresponding receptors and then actively target tumors to release drugs

doi: 10.1016/j.fsi.2024.109795 8 AmoahK.DongX.TanB.ZhangS.KuebutornyeF

Brucein D, a naturally occurring quassinoid, enhances the sensitivity of pancreatic ductal adenocarcinoma (PDAC) cells to gemcitabine (GEM) by promoting the ubiquitin-proteasome-dependent degradation of NRF2 and suppression of the NRF2 signaling pathway [104]
