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Niethammer P, Grabher C, Look AT, Mitchison TJ (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

On the other hand, the inhibition of Nrf2 signaling might be employed to enhance the sensitization of chemoresistant tumors to cytotoxic agents, and in this context, it has recently been reported that brusatol, a compound found in a plant extract, acts as inhibitor of this pathway and may exhibit therapeutic utility [111]

Gene therapy is still at an early stage of development, but our clinical trials have already provided proof-of-principle for sustained clinical efficacy with low toxicity in several patients

As with fish oil, because curcumin has potent anti-inflammatory and antioxidant effects and because virtually all chronic diseases are characterized by these factors, curcumin has been used by clinicians for a wide variety of conditions