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Activation of PGC-1 alters the metabolic phenotype through interactions with nuclear respiratory factor and peroxisome proliferator-activated receptor- [8-10], which leads to increased mitochondrial biogenesis and activity

These free radicals can damage cells, proteins, and DNA, contributing to aging and a host of diseases

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Metabolic Regulation Context Studies explore amylin-related signaling in energy balance, glucose regulation markers, and central appetite pathways [2]