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Inhibition of cholesterol esterification, either by genetic ablation or by pharmacological inhibition of sterol O-acyltransferase 1 (SOAT1) (with avasimibe in micromolar doses), enhances the effector functions and proliferation of CD8 + T cells without affecting CD4 + T cells

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Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death
