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doi: 10.1016/S2213-2600(20)30411-2 242 LeetenKJacquesNLancellottiPOuryC

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Observations in these settings have included: Effects on fibroblast activity in vitro Interactions with extracellular matrix components Influence on cellular repair mechanisms in experimental models Potential involvement in hair follicle cell studies (non-clinical) It is important to note that these findings are derived from preclinical or laboratory-based research and are not conclusive for real-world applications

No injections are needed, and surgery is not involved during this skin-tightening procedure, which is entirely noninvasive