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C., Petrash, J
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accordingly, glutamine synthetase (GS), which promotes glutamine synthesis from glutamate, restrains both M1 macrophage differentiation and antitumor immunity, and its inhibition promotes implanted lung tumors elimination in mice [50, 182]
2 Exposome The exposome (Figure 1) encapsulates all of the environmental (non-genetic) exposures experienced by an individual from an array of dietary, lifestyle, and demographic factors throughout the lifespan that impact health outcomes (Wild, 2005)
