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Description
R.ChenS.BrintonR

As the dominant G-actin sequestering protein in mammalian cells, TB-500 binds globular actin with high affinity (Kd ~0.5 M) through a sophisticated triple-contact mechanism involving Lys-3, Lys-18, and Lys-38 residues, preventing spontaneous actin polymerization while maintaining a readily mobilizable reservoir for rapid cytoskeletal reorganization
Gastrointestinal Health: Given its origin in the gastric system, BPC-157 has been studied for its potential to protect the gut lining, reduce inflammation, and support the healing of ulcers

Human Evidence To Date Publicly available human data consist of a small 12 patient open label intravesical pilot in women with interstitial cystitis non responsive to prior therapy plus anecdotal or preliminary references to other ongoing studies without published results
