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Figure 11 - Examples of acylation reactions

However, this effect is typically less robust than reduction of drug self-administration and is observed with higher doses of agonist than the minimal effective dose required to reduce drug self-administration (Peters and Kalivas, 2006

Redox reactions typically utilize the biologically accessible oxidization states of the metal core to transfer electrons to naturally occurring substrates that are essential for the cancer cell metabolism and therefore induce cell death
