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In summary, TAMs-targeted treatment strategies include suppressing macrophage recruitment and TAM survival and increasing the transformation of M2 macrophages to M1 macrophages

T., Sen, S., Vresilovic, E
To recap, it could be due to: low TSH (low stimulus to the thyroid gland to make more hormones, a pituitary issue rather than a thyroid issue) low T4 low T3 high reverse T3 high free T3 or T4 (causing cellular resistance), or high antibodies causing damage to the thyroid gland However, despite the range of root cause factors that can be behind hypothyroidism, in conventional medicine, the standard treatment for all cases is usually Levothyroxine
10.1038/s41392-022-01232-3 135 LiuZ.YangJ.DuM.XinW