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[10] [12] High-dose ascorbic acid may diminish the therapeutic effects of certain chemotherapeutic agents, such as bortezomib, due to its antioxidant properties

In this regard, the in ovo supplementation of 1% arginine increased maltase and sucrase activities at day 7 post-hatch (45)

What Makes Periorbital Skin So Vulnerable A 2019 clinical assessment published in Clinical, Cosmetic and Investigational Dermatology confirmed that under-eye dark circles correlate with measurably thinner skin, higher hemoglobin index (a marker of vascular prominence), and a higher melanin index all pointing to both vascular and pigmentary contributors rather than just one single cause

The treatment of GSH results in increased enzymatic activities such as SOD, CAT, GPX, GR, MDHAR, and DHAR, which leads to an increase in endogenous AsA and GSH levels, along with increased ratios of AsA/DHA and GSH/GSSG, thus reducing the level of overproduced ROS species (Jung et al., 2019