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c Animal study

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1a) that is conserved in all human SPOC domains except SPOCD1 and is critical for the electrostatic anchoring of phosphorylated serine in CTD by PHF3 SPOC and in SMRT/NCoR by SHARP SPOC (R1248 in PHF3, R3552 in SHARP, Figs
Mechanisms implicated in synaptic plasticity, dendritic spine formation, and hippocampal neurogenesis in rodent models