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Description
The amino-terminal ER-luminal segments of STIM proteins are the Ca 2+ sensing domains by virtue of specific EF-hand domain Ca 2+ binding sites,which are highly tuned to detect small changes in luminal Ca 2+ levels

& Aandahl, E

[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Koganti R, Suryawanshi R, and Shukla D
Segment (d) and its bypass by more than 80 pathways is exhaustively addressed in ref