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Animal studies have emphasized the efficiency of the glymphatic system in purging waste from the brain, with peak effectiveness during sleep [14], particularly at night [204], and reduced efficacy observed in animal models of hypertension [205]

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The unique metabolic characteristic of T cells in liver cancer is that altered T cell metabolism plays different roles in Nonalcoholic Steatohepatitis (NASH), Autoimmune hepatitis (AIH), and Hepatocellular carcinoma (HCC) development