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Description
In therapy, synthetic or bioidentical peptides are introduced, usually by injection but sometimes through capsules, creams, or nasal sprays, to mimic or enhance these natural signals

Deeks ED (2019) Polatuzumab vedotin: first global approval

The clinical features strongly resemble classical EDS (cEDS) with two key differences: (1) the absence of atrophic scarring and (2) autosomal recessive inheritance
Experimental models have shown that DSIP administration increases GABAergic activity while reducing excitatory neurotransmission in cortical and limbic regions
