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[DOI] [PubMed] [Google Scholar] 153.Tentori L., Dorio A.S., Mazzon E., et al

Whereas other NADPH-dependent oxidoreductases expressed in the livers lacking TrxR1, such as carbonyl reductases or NADPHquinone dehydrogenase 20,23 , might contribute to redox homeostasis in the TR/GR-null livers by reducing non-sulfur substrates, our results suggest that disulfide-reducing activities in TR/GR-null livers are not markedly supported by processes other than de novo GSH synthesis
Single-stranded nucleic acids, driven by complementary base pairing, fold into diverse secondary structures and subsequently form well-defined three-dimensional conformations, giving rise to specific functional sites

immune processes such as antigen presentation modulation, cytokine production, lymphocyte proliferation, apoptosis regulation, and enhancement of cytotoxic T cells and NK cells