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doi: 10.1016/j.dadm.2019.03.004

In all studies that showed a beneficial effect on cognitive functions, the participants were trained or highly trained athletes [13, 17, 19]

Clinical trials in patients with metabolic syndrome reveal that L-Carnitine supplementation of 2 g/day for extended periods (25-50 weeks) significantly reduces fasting blood glucose, HbA1c, homeostatic model assessment-insulin resistance (HOMA-IR), inflammatory markers including C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-), and triglyceride levels

The loss of trimethylated histone 3 at lysine residue 27 (H3K27me3) expression due to the inactivation of polycomb repressor complex (PRC2) for mutations of the SUZ12 gene is a diagnostic tool [1,5,80]
