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Additionally, such an effect means that there is a consistent matching of pressure disturbances, i.e., intraocular (intraocular pressure) and extra-ocular (intracranial, portal, caval hypertension, and aortal hypotension)

Chem Res Toxicol 10(8):895905 Ceni E, Mello T, Galli A (2014) Pathogenesis of alcoholic liver disease: role of oxidative metabolism

Currently, there are some hypotheses supporting that patients with BD may have an altered histaminergic system, with upregulated histamine levels in manic phases and downregulated in depression, being their fluctuations closely related to other pathophysiological mechanisms [183]

Macrophage-mediated inflammatory responses in white adipose tissue (WAT) are closely related to metabolic disorders of fat (Macia et al., 2015