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Molecular effects of FDA-approved multiple sclerosis drugs on glial cells and neurons of the central nervous system
Mice were then randomized into three groups ( n =10) and treated by intraperitoneal injection of 25 mg kg 1 per day erlotinib/0.5% w/v methylcellulose and/or 6 mg kg 1 per day EA/1% Tween 80 in distilled water
Butzer, U
So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations
