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Description
Senescence is associated with TRPC3 downregulation, which increases mitochondrial Ca 2+ uptake, mitochondrial depolarization, and ROS production and alters mitochondrial metabolism, thereby promoting the protumourigenic effects of senescence [318]

2519 (sem 425) v

Nevertheless, interestingly, an old study on hematologic malignancies concluded that neither malignancy itself nor its treatment considerably affected CRP responses [800]

Exercise creates the demand
