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Tirzepatide is an FDA-approved medication for type 2 diabetes and chronic weight management, available exclusively as pre-filled injection pens under the brand names Mounjaro and Zepbound

In contrast, cortical microglia largely returned to baseline following cuprizone withdrawal, with full recovery of morphological heterogeneity (p = 0.0025), cell area (p = 0.0096), and density (p = 0.0002) - consistent with a reduced burden of demyelination and debris clearance in this area

We prioritised systematic reviews and studies on the benefits, harms, and cost effectiveness of B 12 supplementation

M1/M2 macrophages in atherosclerosis The inflammatory environment in atherosclerotic lesions seems to be important for their generation and decreased stability leading to thrombosis